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Applied Clinical Research, Clinical Trials and Regulatory Affairs

Author(s): Aisha Alkhaaldi, Majid Al Teneiji, Muhammad Faisal Khanani, Mustafa Baroudi, Altaf Jamil, Omar Trad, Layla Al Reyami and Najam Ahmed Awan

DOI: 10.2174/2213476X0103150707122135

Cite As
Two Cases of Glucose-6-phosphate Dehydrogenase Deficiency Presenting as Symptomatic Methemoglobinemia with Persistently Low Saturations After Fava Bean Ingestion in United Arab Emirates

Page: [176 - 179] Pages: 4

  • * (Excluding Mailing and Handling)

Abstract

We report two cases of one previously healthy child and another known to have G6PD deficiency, who presented with desaturation despite their stable clinical appearance, which later was attributed to methemoglobinemia (MetHb) that was precipitated by fava beans ingestion.

When hemolytic crisis occurs, certain G6PD deficient patients might develop cyanosis and show evidence of concurrent methemoglobinemia.

In conclusion, Methemoglobinemia is a rare but important cause of persistently low saturation.

Keywords: Acute hemolysis, Favism, Glucose-6-phosphate dehydrogenase deficiency, Methemoglobinemia.