Abstract

The microwave-promoted reactions of 5-amino-1,3-disubstituted pyrazoles with benzaldehyde, 4-chloro- and 4-nitrobenzaldehydes are presented. The use of microwave irradiation with variable input power leads to different products, such as Schiff bases, diamine derivatives and bispyrazolo[ 3,4-b;4’3’-e]pyridines in moderate to excellent yields and high purities.

Keywords: Aldehydes, bis-pyrazolo[3, 4-b;4’, 3’-e]pyridines, diamine derivatives, N-heterocycles, microwave assisted synthesis, pyrazoles.