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Current Organic Chemistry

Author(s): Bhaskara Nand, Garima Khanna, Ankita Chaudhary, Anshika Lumb and Jitender M. Khurana

DOI: 10.2174/1385272819666150402221133

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1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU): A Versatile Reagent in Organic Synthesis

Page: [790 - 812] Pages: 23

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Abstract

This review focuses on the catalytic activity of the organic bicyclic amidine base, 1,8-diazabicyclo [5.4.0]undec-7-ene (DBU). It is available commercially, cheap and a homogenous catalyst. It has been used widely in a variety of reactions viz. elimination, esterification, cyclisation, condensation, multicomponent reactions etc.

Keywords: Cycloaddition, DBU, isomerization, MCRs.

Graphical Abstract