Cardiovascular & Hematological Agents in Medicinal Chemistry

Author(s): Julio Herrera

DOI: 10.2174/1871525713666150310112759

Beta-Blockers use for Hypertension in the Elderly

Page: [152 - 159] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

Beta-blockers are considered as suitable drugs to treat essential hypertension also in elderly patients and they are currently recommended for treatment of hypertension, even in older patients, by the ESH/ESC Guidelines. Different meta-analyses and results of some large clinical trials have shown that here is no clinically difference between β-blockers and other drug classes in decreasing high blood pressure in elderly hypertensive patients. The new vasodilating β-blockers, as nebivolol, carvedilol and celiprolol, offer additional important advantages, compared with traditional β-blockers. The cardio-protective effect of β-blockers (except atenolol) is not inferior to that obtained with other drug classes which is independent of age and gender of the patients.

Keywords: Beta-blockers, elderly, hypertension.