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Current Catalysis

Author(s): Erika Balint, Judit Takacs, Maria Balint and Gyorgy Keglevich

DOI: 10.2174/2211544704666150303232225

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The Catalyst-free Addition of Dialkyl Phosphites on the Triple Bond of Alkyl Phenylpropiolates Under Microwave Conditions

Page: [57 - 64] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

As an extension of our earlier study, (E)-alkyl 3- (dialkoxyphosphoryl)-3-phenylacrylates were synthesized by the addition of dialkyl phosphites to the triple bond of alkyl phenylpropiolates under microwave irradiation. The (E)- diastereoselectivity of the monoadducts falls in the range of 84–90%. There was no need to use any catalyst.

Keywords: Alkyl phenylpropiolate, dialkyl phosphite, addition, microwave.

Graphical Abstract