Author(s): Sandra Santos Ribeiro, Suzan Pantaroto de, Patricia Locosque Ramos, João Batista da Cruz and André Luiz Meleiro Porto
Page: [9 - 13] Pages: 5
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This paper describes the bioreduction of four fluoroacetophenones with thermophilic bacteria (Bacillus sp. FPZSP005, B. subtilis FPZSP088, B. licheniformis FPZSP055 and BC-FPZSP051). The reduction reactions were performed under microwave irradiation and the thermophilic bacteria of the Bacillus genus provided moderate conversions to fluoroalcohols with yields in the 26-42% ranges and 5-62% e.e. When the reactions were carried out under conventional heating, they showed high conversions and selectivities (up to > 99% e.e.). This is the first study in the literature on the use of microwave irradiation with thermophilic bacteria applied on biocatalysis.
Keywords: Bacillus, biocatalysis, bioreduction, microwave irradiation.
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