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Letters in Organic Chemistry

Author(s): Yuan-Yuan Yao and Xian-Liang Zhao

DOI: 10.2174/157017861201150112125024

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A Rapid, Efficient Method for Deprotection of Oximes to Carbonyl Compounds with NaClO2 in Water

Page: [73 - 76] Pages: 4

  • * (Excluding Mailing and Handling)

Abstract

A rapid, efficient method for deprotection of oximes to carbonyl compounds is demonstrated by using sodium chlorite (NaClO2) in water. The protocol has been found to be applicable to a wide range of aldoximes and ketoximes with good to excellent yields of the corresponding carbonyl compounds.

Keywords: Sodium chlorite, oximes, carbonyl compounds, aqueous conditions.

Graphical Abstract