Green Synthesis of Phosphorylated Chromenes from Hydroxy Phenones

Page: [176 - 180] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

A simple, efficient and environmentally method for the synthesis of phosphonate derivatives have been considered using the reaction of 2'-hydroxy acetophenone or 1-(6-hydroxy-2-isopropenyl-1-benzofuran-yl)-1-ethanone, malononitrile or ethyl cyanoacetate and trialkyl phosphites or triaryl phosphite in water as the solvent at room temperature.

Keywords: Trialkyl phosphite, ttriaryl phosphite, malononitrile, ethyl cyanoacetate, 2'-hydroxyacetophenone.

Graphical Abstract