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Letters in Organic Chemistry

Author(s): Ardeshir Khazaei, Heidar Ali Alavi Nik and Payam Rahmani

DOI: 10.2174/1570178612666141211224503

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A Comprehensive Comparison Metal Salts Effect on Time and Yield of Quinoxalines Synthesis

Page: [21 - 30] Pages: 10

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Abstract

A new one-pot three-component and highly efficient approach for the synthesis of quinoxaline derivatives was investigated. This was achieved via two methods from the reaction of α-hydroxy ketones or 1,2-dicarbonyl compounds with o-phenylenediamine in the presence of catalytic amount of many metal salt catalysts especially Zn(OAc)2 and mixture of Mn(OAc)2 and Zn(OAc)2.

Keywords: Quinoxaline, 1, 2-dicarbonyl compounds, α-hydroxyketone, metal salts, in-Situ oxidation, one-pot procedure.

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