Abstract

A convenient access to some new and known bis(pyrazolyl)methanes synthesis has been successfully achieved via an alternative Knoevenagel/Michael reaction of aromatic aldehydes and pyrazole-5-one in the presence of Mohr’s salt as a green catalyst. This novel procedure has some advantages such as high efficiency, simplicity, high rate and environmental safety.

Keywords: Green synthesis, Knoevenagel condensation, Michael addition, aqueous media, bis(pyrazolyl)methane, Mohr’s salt.

Graphical Abstract