Abstract

Cystic fibrosis (CF) is a genetic disorder that can lead to death at an early age. CF is characterized by respiratory infection, airway obstruction, inflammation, and eventually end-stage lung failure. CF also damages pancreatic exocrine function resulting in serious complications such as nutritional deficiencies. Current therapy to this multisystem disease requires the practice of both pharmacological and nutritional approaches. Growing evidence shows that bioactive food components, such as polyunsaturated fatty acids, phytochemicals, and antioxidants, have beneficial effects in the management of CF disease. This review will summarize the current status of bioactive compounds in CF therapy.

Keywords: Antioxidant, bioactive food component, cystic fibrosis, functional food, nutraceutical, polyunsaturated fatty acid, phytochemical.

Graphical Abstract