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Letters in Organic Chemistry

Author(s): Fatiha Guenfoud, Raouf Boulcina, Mohammed Laabassi and Paul Mosset

DOI: 10.2174/1570178611666140829214223

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Synthesis of Some New Pyrano[2,3-b]quinolines from 2-chloro-3- formylquinolones and Meldrum's Acid

Page: [736 - 742] Pages: 7

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Abstract

A new series of functionalized pyrano[2,3-b]quinolines have been prepared in three steps from first condensation of 3-formyl-2-quinolones with Meldrum’s acid, then the corresponding olefins have been alkylated using methyl magnesium iodide, and finally the target compounds have been obtained in good yields after hydrolysis.

Keywords: 3-formyl-2-quinolones, knoevenagel condensation, meldrum’s acid, pyrano[2, 3-b]quinolines.

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