Mini-Reviews in Medicinal Chemistry

Author(s): Syed Shoaib Ahmad Shah, M. Ijaz Hussain, M. Kashif Aslam and Gildardo Rivera

DOI: 10.2174/1389557514666140820113055

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Natural Products; Pharmacological Importance of Family Cucurbitaceae: A Brief Review

Page: [694 - 705] Pages: 12

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Abstract

Compounds derived from nature have played a major role in drug discovery. They became the basis for the development of new pharmaceuticals. In this scope, family Cucurbitaceae is a prominent source of secondary metabolites, mainly triterpenoids. In this paper, we provide a brief review of cucurbitane metabolites that exhibit an extensive range of biological actions specifically antidiabetic, anti-inflammatory, cytotoxic, hepatoprotective, and antiparasitic effects.

Keywords: Antibacterial, antiparasitic, Cucurbitaceae, momordica, natural products, pharmacological activity.