Current Organic Synthesis

Author(s): Gangliang Huang and Qilin Tang

DOI: 10.2174/1570179411666140623223120

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Synthesis of Allosamidin and its Analogues

Page: [696 - 700] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family 18 chitinases, and it is confirmed to have biological activities against insects and fungi. The solid/liquid phase syntheses of allosamidin 1 and its analogues have been developed in recent years, and these compounds can be obtained by iterative glycosylation reactions, catalytic hydrogenation, acetylation, deacetylation, or photolysis, respectively.

Keywords: Allosamidin, analogues, recent development, synthesis.