Current Drug Targets

Author(s): Marianna Abelli, Claudia Martini, Stefano Pini, Camilla Gesi and Giovanni B. Cassano

DOI: 10.2174/1389450054546015

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The Role of Newer Antiglutamatergic Agents as Mood-Stabilizers in Bipolar Disorder

Page: [607 - 614] Pages: 8

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Abstract

In bipolar patients, maintenance treatment with anticonvulsive agents is a valid alternative to lithium. These agents have widely varying mechanisms of action. Some of these medications focus on the current understanding of antiglutamatergic mechanisms of action and their treatment implications for bipolar disorders.

Keywords: glutamate, anticonvulsants, depression, bipolar disorder