The Natural Products Journal

Author(s): Peter Kovacic and Ratnasamy Somanathan

DOI: 10.2174/2210315504666140512220028

DownloadDownload PDF Flyer Cite As
Cannabinoids (CBD, CBDHQ and THC): Metabolism, Physiological Effects, Electron Transfer, Reactive Oxygen Species and Medical Use

Page: [47 - 53] Pages: 7

  • * (Excluding Mailing and Handling)

Abstract

In recent years, cannabinoids, particularly cannabidiol (medical marijuana), have attracted considerable attention. This review addresses various aspects including metabolism. Other cannabinols of interest are THC and the hydroxyl quinone metabolite. Physiological influences are addressed, particularly anticancer action, receptors, antioxidants, and neurological effects. A unifying mechanism is invoked based on electron transfer, reactive oxygen species and oxidative stress.

Keywords: Cannabinoids, cannabidiol, metabolism, therapy, toxicity, electron transfer, reactive oxygen species.