Abstract

This review is dedicated to enantioselective methods for the generation of carbohydrate-based lead compounds for drug research. Selected examples encompassing imino sugars, bicyclic imino sugar-type alkaloids such as castanospermine, swainsonine, or alexine, as well as macrolide glycosides are covered and discussed.

Keywords: Alkaloids, carbohydrates, enantioselective synthesis, imino sugars, macrolide glycosides.

Graphical Abstract