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Mini-Reviews in Medicinal Chemistry

Author(s): Rajeev Kumar, T.S. Sirohi, Hariram Singh, Ramji Yadav, R.K. Roy, A. Chaudhary and S.N. Pandeya

DOI: 10.2174/1389557514666140131111837

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1,2,4-Triazine Analogs as Novel Class of Therapeutic Agents

Page: [168 - 207] Pages: 40

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Abstract

1,2,4-Triazine nucleus is a prominent structural core system present in numerous pharmacologically active compounds. Till date, various 1,2,4-triazine analogs, possesing a wide range of potent pharmacological activities, have been reported. This review is an attempt to compile the medicinal chemistry aspects of various synthesized 1,2,4-triazine analogs reported so far.

Keywords: Anticancer activity, anticonvulsant activity, antimicrobial activity, 1, 2, 4-triazine.