Mini-Reviews in Medicinal Chemistry

Author(s): Rajeev Kumar, Amar Deep Singh, Jitendra Singh, Hariram Singh, R.K. Roy and Anurag Chaudhary

DOI: 10.2174/1389557513666140103111017

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1,2,3-Triazine Scaffold as a Potent Biologically Active Moiety: A Mini Review

Page: [72 - 83] Pages: 12

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Abstract

1,2,3-Triazine is an interesting class of heterocyclic compounds. Various synthetic analogs of 1,2,3-triazine have been prepared and evaluated for many pharmacological activities in different models with desired findings. Some analogs have shown potent pharmacological activity and may be considered as lead molecule for the development of future drugs. This review is an attempt to organize the chemical and pharmacological aspects of 1,2,3-triazine analogs reported till date systematically since 1970.

Keywords: Anticancer activity, antimicrobial activity, antiprotozoal, in vivo, 1, 2, 3-triazine.