Current Topics in Medicinal Chemistry

Author(s): Asteria Luzardo-Alvarez, Eduardo Sobarzo-Sanchez, Jose Blanco-Mendez and Francisco J. Otero-Espinar

DOI: 10.2174/1568026613666131219125419

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Cyclodextrin-Based Polysaccharidic Polymers: An Approach for the Drug Delivery

Page: [542 - 551] Pages: 10

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Abstract

The aim of the present review is to give an overview of a new class of polysaccharidic CD-based systems and to address the use of these systems in drug delivery. First, we review miscellaneous methods to obtain and synthesize the structural modification of natural polysaccharides, mainly, with cyclodextrins. In a second part of this review, we provide a summary of recent findings not only in the field of drug delivery, but in also how these systems have displayed different applications in the biomedical and pharmaceutical fields.

Keywords: Cyclodextrins, drug delivery system, drug solubility, methods of preparation, pharmaceutical applications, polysaccharides.