Letters in Organic Chemistry

Author(s): Mahgol Tajbakhsh, Yousef Ranjbar, Abdolhosein Masuodi, Parizad Rezaee, Mahmood Tajbakhsh and Zari Fallah

DOI: 10.2174/1570178610666131128234939

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Ultrasonic-Assisted Surface- Modification of Nanosilica Chloride and its Use for Synthesis of 3,4- Dihydropyrimidinones

Page: [361 - 367] Pages: 7

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Abstract

Nanosilica chloride was prepared with modification of the surface by applying ultrasonic irradiation and has been employed as an efficient, heterogeneous and effective catalyst in the preparation of 3,4- dihydropyrimidinones (DHPMs) under solvent-free conditions. Simple workup procedure, short reaction time, and good to excellent yield of the product, are other advantages of this catalyst.

Keywords: Nanosilica chloride, multicomponent reactions, ultrasonic irradiation, Biginelli reaction, dihydropyrimidinones, heterogeneous catalyst.