Abstract

A significant proportion of drugs present in market, are poorly soluble. Formulation development of these drugs is also a demanding challenge. Nanosuspensions have revealed their potential to problems, associated with poorly soluble drugs. Media milling and high pressure homogenization techniques have been used extensively for producing the nanosuspensions. This article reviews the various aspects related to nanosuspensions and their potential as a strategic approach for poorly soluble drugs.

Keywords: Drug delivery, Nanosuspension, Nanosuspension formulations, Poor soluble drugs, Saturation solubility, Stability