Author(s): Philip H. Elsinga and Rudi A.J.O. Dierckx
Page: [2268 - 2274] Pages: 7
* (Excluding Mailing and Handling)
This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria are important to consider before starting to develop novel PET-tracers. Principles and latest trends in 11C and 18F-radiochemistry are summarized. In addition an update of some new developments in regulatory aspects is supplied.
Keywords: PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18.
Download PDF Flyer