Abstract

Fluoride-free Hiyama cross-coupling reactions of phenyltrimethoxysilane with aryl halides were performed in water using sodium hydroxide as the activator at 110 °C. The reactions, catalyzed by PVP stabilized colloidal palladium nanoparticles, show enhanced rate under microwave heating and proceed quickly (6 min).The progress of the reactions was monitored by GC-MS and parameters such as catalyst concentration, effect of base, recyclability etc. were investigated. Excellent yields were obtained with a variety of substrates and the products, after isolation, were characterized by ¹H NMR.

Keywords: Hiyama cross-coupling, Microwave heating, Pd (0)–PVP Nanoparticles, Reaction catalyzed.