Current Cancer Therapy Reviews

Author(s): Adey Hasan, Aaysha Kapila, Thomas Barklow, George Youngberg, Guha Krishnaswamy and Bhuvana Guha

DOI: 10.2174/1573394711309020007

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Refractory Cough as a Remote Manifestation of Retroperitoneal Liposarcoma

Page: [147 - 150] Pages: 4

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Abstract

Retroperitoneal liposarcoma is often asymptomatic but sometimes attention is drawn to the neoplasm due to clinical manifestations. These include fever, flu-like symptoms, nausea or vomiting due to pressure or hypoglycemia related to paraneoplastic disease. We present a rare case of a massive retroperitoneal liposarcoma presenting with refractory dry cough. The patient underwent resection of the mass with complete resolution of her cough. Histopathological examination of the mass demonstrated a well-differentiated tumor with myxomatous features. No evidence of metastatic disease to the lungs was observed. This case points to the need for a thorough and careful evaluation of unexplained cough.

Keywords: Liposarcoma, retroperitoneal, refractory cough.