Current Catalysis

Author(s): Santosh V. Goswami, Sunil S. Wagh, Shrikant S. Pendalwar and Sudhakar R. Bhusare

DOI: 10.2174/22115447113029990012

A Facile and Convenient Approach for the One-Pot Synthesis of Naphtho- 1,3-oxazine Derivatives

Page: [244 - 248] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

A protocol describes the synthesis of naphtha-1,3-oxaizine derivatives via one-pot multi-component reaction of α-naphthol, formaldehyde and various substituted anilines catalyzed by L-proline as an efficient catalyst. A method offers delightful advantages such as mild reaction conditions, environmentally benign, easy experimental workup and good to excellent yields.

Keywords: Naphthoxazine, α-Naphthol, Formaldehyde, Aniline, L-proline.