Abstract

Coordination compounds based on bis-quinolizidine derivatives as ligands are described from the viewpoint of their spectroscopic and structural properties. The metal ligand ability of C2 substituted sparteines and bis-quinolizidine Noxides is discussed in order to establish how far the presence of a substituent at α position to the nitrogen atom, involved in the formation of metal complexes or N-oxide function, influences the course of the complexation reaction and geometry of the complexes. The results are confronted with theoretical calculations. Potential pharmacological properties of selected complexes are also determined.

Keywords: Bis-quinolizidine N-oxides, theoretical calculations, metal complexes, sparteine derivatives, spectroscopic properties, x-ray structure.