Pyrrole is one of the main five membered heterocyclic systems reported for its various chemotherapeutic activities. Subsequently, pyrroles have been highlighted as the important biologically active scaffolds. This review focuses on the synthesis, reactions and pharmacological activity associated with pyrroles, and its derivatives. Microwave-assisted reactions are also covered to understand green chemistry aspects of pyrrole and its derivatives. Various pharmacological applications are discussed critically to assess the importance of the compounds.
Keywords: Pyrroles, Microwave synthesis, Applications.