Author(s): Qi He, Zhouyu Wang, Shan Qian, Zhenju Jiang, Jianhui Li, Dehong Jiang and Wensi Ai
Page: [369 - 373] Pages: 5
* (Excluding Mailing and Handling)
In the absence of any additional catalysts, a series of aromatic amines were alkylated with a range of aromatic and aliphatic aldehydes. Moderate to excellent isolated yields (up to 94%) were obtained under mild conditions. Simultaneously, the reaction time dramatically shortened from hours to minutes when the Microwave technique was used.
Keywords: Catalyst-free, reductive amination, aldehydes, Hantzsch ester.
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