Recent Patents on Inflammation & Allergy Drug Discovery

Author(s): Shyamji Shukla, Harshita Shukla, Suneel Kumar, Ravindra P. Aharwal, Vaibhav K. Gupta and Sardul S. Sandhu

DOI: 10.2174/1872213X11307020005

Allergy and Inflammation: An Immunological and Therapeutic Approach

Page: [135 - 150] Pages: 16

  • * (Excluding Mailing and Handling)

Abstract

All organisms are protected by their immune system but occasionally this system overreacts leading to allergic and inflammatory reactions in the body. These reactions are the starting points of various diseases like asthma, eczema and urticaria etc. They involve activation of T cells, release of histamines, toxic chemicals from mast cells and eosinophils respectively. Several chemically and naturally synthesized therapeutic agents are available for the treatment of these immunological diseases. The present review provides a detailed account of mechanism of allergic and inflammatory reactions, its types and various treatment strategies with a special focus on some recent patents in this field.

Keywords: Allergy, antibodies, hypersensitivity, IgE, inflammation, macrophage, therapeutic.