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Letters in Organic Chemistry

Author(s): Davood Habibi, Hesam Sahebekhtiari, Mahmoud Nasrollahzadeh and Ahmad Taghipour

DOI: 10.2174/1570178611310030012

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A Very Simple, Highly Efficient and Catalyst-free Procedure for the NFormylation of Amines Using Triethyl orthoformate in Water Under Ultrasound-irradiation

Page: [209 - 212] Pages: 4

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Abstract

N-Formylation of amines has efficiently been carried out in excellent yields by treatment of amines with triethyl orthoformate in water under ultrasound irradiation. The process is remarkably simple and environmentally benign.

Keywords: Amines, Aqueous medium, Catalyst-free, N-formylation, Triethyl orthoformate, Ultrasound irradiation