Current Organic Chemistry

Author(s): Laura F. Solares and Cesar Mateo

DOI: 10.2174/1385272811317070008

Improvement of the Epoxide Hydrolase Properties for the Enantioselective Hydrolysis of Epoxides

Page: [744 - 755] Pages: 12

  • * (Excluding Mailing and Handling)

Abstract

Epoxide hydrolase (EH) is an interesting tool in different processes of organic chemistry. In this review the different available techniques to improve the properties (activity, stability and selectivity) and to enhance the applicability of this enzyme at a large scale will be studied. In particular, the review focuses on immobilization techniques and different examples are presented using different methodologies.

Keywords: Epoxide hydrolase, improved properties, enzyme immobilization, biocatalysis.