Author(s): Jose A. Boga, Maria de Ona, Santiago Melon, Marta E. Alvarez-Arguelles, Ana Morilla and Ana Coto-Montes
Page: [115 - 119] Pages: 5
* (Excluding Mailing and Handling)
In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.
Keywords: Immunity, MAVS, mitochondria, viral infection
