Current Drug Delivery

Author(s): Zuhre Senturk

DOI: 10.2174/1567201811310010014

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Analysis of Carcinogenic Polycyclic Aromatic Hydrocarbons (PAHS): An Overview of Modern Electroanalytical Techniques and their Applications

Page: [76 - 91] Pages: 16

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Abstract

A number of Polycyclic Aromatic Hydrocarbons (PAHs) have been shown to be toxicants, and induce carcinogenic and immunotoxic effects. Since PAHs are often present in low concentrations and it may be difficult to determine them in complex matrices, it is therefore essential to use powerful analytical tools to separate and identify the analyses in the samples. In this paper, initially, a short description of the principles, instrumentation, and use of common extraction and analytical techniques for PAH pollutants and their metabolites will be made in light of the previously reported works and major reviews. Special attention will be given to the use of modern polarographic and voltammetric techniques on the mercury and different types of solid electrodes, together with their some practical applications. The main drawbacks and limitations of these methods will also be discussed.

Keywords: Analysis, application, common methodologies, electroanalytical techniques, polycyclic aromatic hydrocarbons (PAHs)