Current Medicinal Chemistry

Author(s): M. Asadian-Birjand, A. Sousa-Herves, D. Steinhilber, J.C. Cuggino and M. Calderon

DOI: 10.2174/0929867311209025029

Functional Nanogels for Biomedical Applications

Page: [5029 - 5043] Pages: 15

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Abstract

This review addresses current and future perspectives of nanogel technology for nanomedicine. The synthetic methodologies and material properties of nanogels prepared by chemical meanings are discussed in detail, and examples that illustrate the different methodologies are presented. Applications in the fields of drug and gene delivery, smart imaging modalities, responsive materials, and multivalency as a therapeutic approach highlight the enormous potential of the functional nanogels as novel polymeric platforms for biomedicine.

Keywords: Biomedicine, drug delivery, functional polymer, imaging, multivalency, nanocarrier, nanogel, polymer therapeutics, responsive polymer