Author(s): Cortez-Maya Sandra, Cortes Cortes Eduardo, Hernandez-Ortega Simon, Ramirez Apan Teresa, Nieto Camacho Antonio, Irina V. Lijanova and Martinez-Garcia Marcos
Page: [611 - 618] Pages: 8
* (Excluding Mailing and Handling)
A series of 5-aryl-1,4-benzodiazepines with chloro- or fluoro-substituents in the second ring have been synthesized and their anti-inflammatory, myeloperoxidase and anticancer properties studied. The synthesized compounds showed potential anti-inflammatory and anticancer activities, which were enhanced in the presence of a chloro-substituent in the second ring of the 5-aryl-1,4- benzodiazepine.
Keywords: Anticancer activity, Anti-inflammatory, 1, 4-benzodiazepines, Myeloperoxidase
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