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Current HIV Research

Author(s): Paria Mirmonsef, Laurie Krass, Alan Landay and Gregory T. Spear

DOI: 10.2174/157016212800618165

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The Role of Bacterial Vaginosis and Trichomonas in HIV Transmission Across The Female Genital Tract

Page: [202 - 210] Pages: 9

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Abstract

Bacterial vaginosis (BV) and Trichomonas vaginalis (TV) infections are both very common and are associated with increased risk of sexual transmission of HIV. There are several mechanisms by which BV and TV could affect susceptibility including inducing pro-inflammatory cytokines and disrupting mucosal barrier function. This review highlights recent advances in our understanding of how these genital conditions lead to an increased risk of HIV infection in women.

Keywords: Bacterial vaginosis, HIV, Inflammation, Trichomonas vaginalis.