Abstract

A convergent chiral pool approach for the total synthesis of xestodecalactones B and C was demonstrated in which intramolecular acylation reaction constituted the key step. Synthetic and spectroscopic studies reported herein, suggested that the previously assigned structures of xestodecalactone B and C be interchanged.

Keywords: Xestodecalactone B and C, Chiral pool, Intramolecular acylation, Hydroboration, Pinnick oxidation, Revision of absolute configuration