Current Organic Chemistry

Author(s): Jorge A.R. Salvador, Samuel M. Silvestre and Vania M. Moreira

DOI: 10.2174/138527212800564204

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Recent Developments in Oxidative Processes in Steroid Chemistry

Page: [1243 - 1276] Pages: 34

  • * (Excluding Mailing and Handling)

Abstract

Oxygenated steroids are bioactive compounds and valuable intermediates in the synthesis of biologically active products and APIs. This review will cover the literature from 2005/06 to the present concerning allylic oxidation, epoxidation and syn-dihydroxylation of alkenes, alcohol oxidation, and remote functionalization reactions of steroidal substrates.

Keywords: Alcohol oxidation, Allylic oxidation, Catalysis, Epoxidation, Oxidative processes, Remote functionalization, Steroids, syndihydroxylation, ∆5-7-ketones, N-hydroxydicarboxylic acid