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Current Organic Synthesis

Author(s): Mario Ordonez, Jose Luis Viveros-Ceballos, Carlos Cativiela and Alicia Arizpe

DOI: 10.2174/157017912801270595

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Stereoselective Synthesis of α-Aminophosphonic Acids Analogs of the 20 Proteinogenic α-Amino Acids

Page: [310 - 341] Pages: 32

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Abstract

This review describes the synthesis, biological interest and importance of the α-aminophosphonic acids analogs of the 20 proteinogenic α-amino acids. Special attention is devoted to those stereoselective procedures that allow the synthesis of the required compounds in enantiomerically pure form.

Keywords: α-Aminophosphonic acids, α-aminophosphonates, α-amino acids, stereoselective synthesis, biological activity, resolution