Current Drug Metabolism

Author(s): Cheng Wang, Jing Wang, Tiezhu Chen, Zhiqiang Luo, Xuemei Yang, Xiongfei Pan, Yunfeng Lin, Zhiyong Qian and Xiaoxiao Cai

DOI: 10.2174/138920012800166508

Absorption, Pharmacokinetics and Disposition of Biodegradable Nanoscale Preparations

Page: [429 - 439] Pages: 11

  • * (Excluding Mailing and Handling)

Abstract

Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. This article aims to review the absorption, pharmacokinetics, distribution properties and toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice.

Keywords: Liposomes, micelles, nanoparticles, PLGA, SLN, passive targeting, active targeting