Abstract

G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.

Keywords: G-quadruplex, DNA, small molecules, luminescent probes, detection, diagnostics, telomere, topologies, propeller, emission