Current Aging Science

Author(s): Lei Li, Yuhao Li, Dongyan Chen, Jinping Shao, Xin le Li and Chen Xu

DOI: 10.2174/1874609811003010043

Fishing for Age-Related Visual System Mutants: Behavioral Screening of Retinal Degeneration Genes in Zebrafish

Page: [43 - 45] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

The zebrafish (Danio rerio) has recently become a mainstream model system for genetic studies of human diseases, such as neurological degenerative diseases, heart diseases, immuno-system disorders, etc. In this article, we will review some recent findings of the usefulness of zebrafish as a model vertebrate for behavioral screening of mutations in vertebrate visual system, for example, genes involved in age-related retinal degeneration.

Keywords: Neural degeneration, zebrafish, retina, mutation