Abstract

Intelligent hydrogel, also known as smart hydrogels, are materials with great potential for development in drug delivery system. Intelligent hydrogel also has the ability to perceive as a signal structure change and stimulation. The review introduces the temperature-, pH-, electric signal-, biochemical molecule-, light- and pressure- sensitive hydrogels. Finally, we described the application of intelligent hydrogel in drug delivery system and the recent patents involved for hydrogel in drug delivery.

Keywords: Drug delivery, hydrogel, intelligent, patents, stimuli-responsive properties, Temperature-Sensitive Hydrogels, pH-Sensitive Hydrogels, Electric Signal-Sensitive Hydrogels, Light-Sensitive Hydrogels, Pressure-Sensitive Hydrogels