Letters in Organic Chemistry

Author(s): Angel Garcia-Munoz, Jaime Gonzalez, Jessica Trujillo-Reyes, Raul A. Morales-Luckie, Victor Sanchez-Mendieta, Carlos Gonzalez, Aydee Fuentes and Erick Cuevas-Yanez

DOI: 10.2174/157017812800167457

Alkyne-Azide Cycloaddition Catalyzed by Fe-Cu Nanoparticles

Page: [160 - 164] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of catalytic amounts of Cu-Fe nanoparticles. The process represents many advantages because it does not require additional bases or reductants, and this is carried out under ambient pressure and temperature with good yields.

Keywords: 1,2,3-triazoles, alkynes, azides, nanoparticles, CuAAC, phenylacetylene, cycloaddition, bromide, sodium, aqueous mixture