Abstract

Copper-catalyzed nitration of arylboronic acids has been developed with nitrite salts as nitrating agent under mild conditions. This process provides an efficient and practical method for the synthesis of nitro aromatics, due to its simple experimental procedure and its use of convenient and inexpensive copper catalyst.

Keywords: Arylboronic acids, copper catalyst, nitration, nitroaromatics, organic synthesis, pharmaceuticals, iodides, chlorotrimethylsilane, oxidative, cross-coupling