Letters in Organic Chemistry

Author(s): Shengqian Jiang, Zhouyu Wang, Zhenju Jiang, Jianhui Li, Shulin Zhou and Long Pu

DOI: 10.2174/157017812799304006

Ritter Reaction in Subcritical Water: An Efficient and Green Method for Amides Synthesis

Page: [24 - 28] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

Ritter reaction was carried out efficiently in subcritical water with catalytic amount of trifluoromethanesulfonic acid. The amides were formed in good to excellent yields from secondary alcohols and tert-butanol with various nitriles.

Keywords: Alcohol, amide, nitrile, ritter reaction, subcritical water, trifluoromethanesulfonic acid, chloride, boron trifluoride, sulfuric acid, silica sulfuric acid