Letters in Organic Chemistry

Author(s): Naveenkumar R. Chepyala, Rajashaker R. Durgi, Lakshmi K. Tatini, Gottumukkala V. Subbaraju, Rama M. Hindupur and Muralimohan R. Dhanvada

DOI: 10.2174/157017811799304322

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Quinolone Dimers as Potential Antibacterial Agents

Page: [637 - 643] Pages: 7

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Abstract

A series of novel 6-fluoro1,4-dihydro-4-oxo-3-quinoline carboxylic acid dimers (34-37), were synthesized as potential antibacterial agents from commercially available fluoro benzoic acids.

Keywords: 2,3,4,5-Tetraflurobenzoic acid, 2,4,5-Trifluoroacetophenone, anti bacterial agents, regiospecific dimeric cyclisation, STERMOL length, quinoline carboxylic acid dimers, cyclopropyl, ciprofloxacin., methylene, ofloxacin