Abstract

A mild, efficient and highly convenient protocol is reported for the synthesis of a series of polyphenolic amides using ferric exchanged montmorillonite as a strong solid acid catalyst. This heterogeneous catalyst has an advantage of a strikingly simple work up procedure over conventional homogeneous acids. The catalyst is recoverable and recyclable.

Keywords: Amidation, montmorillonite, phenolic acids, polyphenolic amides, esters, medicine, antibacterial, antioxidant, anti-inflammatory, antimutagenic