Abstract

[MPSIm]+CF3COO- ionic liquid is an efficient green catalyst for the one-pot, three-component Mannich-type reaction of aromatic aldehydes, aromatic amines and cyclohexanone. The reaction was completed within 5-60 min to give the corresponding β-amino ketones in 82-98% yield at room temperature. The catalyst can be recycled at least four times without significant decrease in activity.

Keywords: Mannich-type reaction, β-amino ketones, synthsis, ionic liquid, catalysis, cyclohexanone, polystyrene-supported, acetophenone, non-inflammability, dodecylbenzenesulfonic